Choline is an essential nutrient that’s involved in the health of every cell in your body. Read more to find out the best choline supplements of 2022.
Choline is a nutrient that plays a key role in many vital bodily functions. It’s found naturally in foods such as eggs, liver, and broccoli, but it’s also sold as a supplement. While you can get all the choline you need from eating healthy foods regularly, some people prefer to take supplements for convenience or increased effectiveness (and there are some benefits). But which choline supplement should you choose? Read on for everything you need to know about this essential nutrient and how it can help improve your health:
What is choline?
Choline is a water-soluble vitamin that is essential for brain and neurological function. It’s found in foods like egg yolks, beef liver, legumes, and cauliflower.
Choline plays an important role in the development of brain cells and their connections to other nerve cells. Choline also helps regulate the body’s fats and glucose (blood sugar) use.
How much do we need?
The recommended daily choline intake is 550 mg for adults, but this number increases as you age. It can range from 500 mg to 550 mg in people aged 19-50 and goes up to 550 mg for those aged 51 and up. Pregnant women should consume 450-550 milligrams per day while breastfeeding mothers should be taking 450 milligrams per day.
Additionally, men need more choline than women; they need 425-550 milligrams per day versus the 350-425 that females need. Pregnant or breastfeeding men also require slightly more than their female counterparts (375 milligrams).
Choline requirements vary based on your age and health condition; if you have diabetes or heart disease (or are at risk for developing either), you’ll likely need more choline than someone without these conditions does for your body systems to function properly. People who lead stressful lifestyles may also require additional dietary sources of B vitamins like folic acid or vitamin B6. These nutrients act as cofactors with acetylcholine during nerve transmission and help maintain a healthy brain function throughout life.
Check out the Best Choline Supplements
Choline is a water-soluble vitamin that has a lot of essential jobs in the body, like helping neurotransmitters work and preventing memory loss. You’ve probably heard of “cholinergic” pathways, which are brain pathways that use acetylcholine as a neurotransmitter. While other kinds of cholinergic receptors (e.g., muscarinic) and other enzymes are involved in making acetylcholine, it will always be an essential part of your brain’s functioning—and taking choline supplements can help make sure you’re getting enough!
1. Nested Naturals Choline

Nested NaturaL capsules contain a very pure form of cholinergic acid (cholamine), which is one of the most important neurotransmitters for brain health. They’re made from 100% natural ingredients, including organic brown sugar cane juice, coconut oil, sunflower lecithin, and a flaxseed meal.
It has so many positive qualities that we think it deserves to be at the top of our list. Its strength lies in its lack of flaws.
2. Standard Process Choline

Standard Process manufactures a 175 mg choline dietary supplement using only natural, high-quality, and pure botanical extracts. It’s one of the best supplements available for sale today.
These tablets contain just three active pharmaceutical substances (APSs), but they’re able to deliver a high dose of cholinium bitartrate, which is one of the most effective APSs available. They’re also easy to swallow because they don’t require any additional excipients.
3. Doctor Recommended Supplements Choline

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Doctor-recommended supplements make one of the best high-doses of cholinergic supplements available, with 500 mg per serving. It contains no artificial ingredients, and brown sugar is the only other thing in each serving.
If you’re taking a cholinergic drug, you may want to take 1g daily. However, if you don’t normally consume enough cholinesterase inhibitors (cholines), you probably won’t benefit from 500mg daily.
4. Standard Process Choline

Standard Process Cholinestatte is a great choice for people who need a moderate dose of cholinergic supplements. It delivers 175 mg of cholinergic compounds per tablet, which makes it a good option for anyone looking for a moderate dose.
5. Now Choline & Inositol

Now Choline & Inositol delivers a mixture of choline and inositol at 250 milligrams per serving.
The capsules are not suitable for strict vegetarians. However, if you don’t mind having animal products in them, you could choose between two options. One option has no additional ingredients besides gelatin, whereas the second contains both inositols and cholinium.
6. Nusapure Choline

Nusapure offers a high-quality choline supplement made from natural sources. It comes in capsules and delivers a whopping 325mg of choline per serving. While the product isn’t quite as clean as other options, it’s still a decent choice.
7. Bulk Supplements Pure Choline Bitartrate

BulkSupplements Pure Choline Bitartrate is another supplement that has been available for years in both liquid and capsule form.
You need a good quality product if you make your meal replacements, shakes, or nootropics. Most people will prefer to buy pre-made products instead of making them themselves.
To measure the choline required for your dog, you’ll first want an extremely accurate scale.
8. GNC Choline

GNC Choline contains 250 mg of cholinium chloride, which is a decent dose for most people, but it also includes some extras, like a thickening agent called “Glyceryl Stearate” (also known as “E420”).
Suppose you need a product with 250 milligrams of choline per serving, and it’s vegan-friendly because of its cellulosic capsule. In that case, you might be interested in trying Cholamine Plus by Pure Encapsulations. However, if you prefer cleaner supplement designs, you might be better off looking for another option.
9. Best Naturals Choline

BestNaturals has a cholinergic formula that contains 265 mg of choline. While this may be a decent dose for some people, it’d probably be better if they had something closer to 500 mg of choline.
Furthermore, tablets contain a lot of binders and other additives that make them heavy on extras. Other choline products available outperform them on multiple levels.
10. KRK Supplements Choline-900

Despite the name, KKR Supplements only delivers 450 milligrams of cholinium chloride (cholinesterase inhibitor) per capsule—the recommended serving size for adults is two capsules.
Choline is an essential nutrient that most people don’t get enough of. However, adults’ recommended daily allowance (RDA) is quite high. Taking a multivitamin containing choline is probably a good idea for most people.
Who should buy choline?
If you’re interested in taking a supplement that may help improve cognitive functions and boost your brain power, consider taking a choline supplement. Choline is a chemical compound that helps produce acetylcholine, an important neurotransmitter. It has been shown to decrease the accumulation of fat in your livers.
At least some circumstantial evidence suggests that choline supplementation might help restore normal levels of fat metabolism in people who suffer from nonalcoholic fatty livers.
Choline supplements may not be safe for people who already have alcoholic hepatitis. So, before taking them, consult your physician first.
Choline supplements may be safe for most people with fatty liver disease, but some people who take certain drugs may need to discuss them with their doctors before using them.
Choline is also important for people who want to boost their brain power, either with nootropics or to keep their minds sharp as they get older. It’ll help them produce more acetylcholine, one of the key neurotransmitter molecules in the human body.
Choline plays a vital role in developing and maintaining neurons in the brain. Therefore, the strongest evidence for its use is likely for cognitive functions.
Benefits of choline supplements
Choline is an essential nutrient that plays a key role in many bodily functions. As we age, our body’s ability to produce choline decreases. This can lead to many health problems like cardiovascular disease and diabetes.
Choline supplements are the ideal way to ensure your body receives enough choline for optimal health and wellness. You can find them in everything from dietary supplements and energy drinks to sports nutrition products, which makes it easy for anyone to benefit from this nutrient!
Lowers the risk of cardiovascular disease
Choline helps reduce cardiovascular disease risk by lowering bad cholesterol and heart attack risks. Choline also improves insulin sensitivity, which is important for regulating blood glucose levels and preventing diabetes; it also lowers triglyceride levels, which may reduce your risk for stroke or atherosclerosis.
Helps in boosting cognition during old age
Choline is a substance that the body uses to make acetylcholine, which improves memory and brain development.
It’s also essential for the health of your brain and nervous system.
Helps in the early brain development of babies
Choline is an essential nutrient that helps develop the central nervous system. It also helps develop the brain, spinal cord, eye retina, muscles, skeleton, and fatty tissue. Since choline is important for a healthy pregnancy and a baby’s early life, expectant mothers should take it as a supplement during their pregnancy.
Reduces symptoms of depression
Choline is an essential nutrient, but it’s not well understood. It has a role in cell membranes and is a precursor of acetylcholine, which is involved in learning and memory.
Choline supplements may help reduce depression symptoms.
May help in weight loss
- Choline is a key component of cell membranes and neurotransmitters, which are all responsible for helping communicate information throughout your body. It’s also a precursor to the formation of acetylcholine, a neurotransmitter that can help with learning and memory. Choline supplements have improved memory in older adults when taken alongside vitamin B12.
- If you are trying to lose weight but feel like your diet isn’t working as well as you hoped it would be, consider adding some choline supplements into your daily routine. One study on obese women found that taking 500 milligrams (mg) per day of choline citrate significantly reduced triglyceride levels after only eight weeks.
Choline is an essential nutrient that plays a key role in many bodily functions.
It is a water-soluble vitamin that plays a key role in many bodily functions, including maintaining cell membranes, building and transporting fatty acids, producing bile to digest fats, helping to regulate the production of cholesterol and other lipids, and supporting the nervous system.
It is also an essential nutrient for liver function and helps with memory function by converting it into the neurotransmitter acetylcholine. Choline supplements are used for treating liver disease (hepatic encephalopathy), mood disorders (depression), ADHD symptoms in children or adults with intellectual disabilities, increasing lifespan in rats (by preventing premature death from liver cancer cells), protecting against heart disease by reducing low-density lipoprotein levels which can lead to clogged arteries or hardening of arterial walls due to plaque buildup over time – this can cause chest pain when exercising vigorously (angina pectoris).
Choline supplements are a popular way to boost your brain power and improve your mental health. You can find them in many forms, including pills, capsules, tablets, and powder. Many people who use choline supplements also experience side effects from using them. These include sweating and body odor that smells like fish. These side effects may be caused by excess choline in your system.
Choline Side Effects and Warnings
Choline is a type of B vitamin found in many foods, including eggs, meat, and fish. Supplements prevent and treat memory problems, liver disease, and high cholesterol.
Side effects from taking choline include:
Too Much Choline May Cause Fungal Infections
Choline is an essential nutrient that helps with brain function and memory. Choline is also a component of lecithin, acetylcholine, phosphatidylcholine, and sphingomyelin. Getting enough choline in your diet is important because a deficiency can lead to fatty liver disease or depression. However, too much choline may cause a fungal infection called aspergillosis.
Aspergillosis is caused by fungi (or mold) that thrive on decaying plants or animals like dead mice or birds in your home attic. Aspergillus fungi are common indoor molds that grow on grains such as cereal and bread products; nuts like peanuts and pistachios; dried fruit such as raisins; seeds such as sunflower seeds and popcorn kernels; flours made from wheat flour, including pasta made from durum wheat semolina pasta sheets which must be reheated before serving otherwise they’ll spoil quickly because they contain natural oils found inside these foods so eating them raw causes nausea within minutes after ingestion due to indigestion symptoms caused by salmonella bacteria found inside chicken nuggets sold at fast food restaurants located around America today!
High Doses of Choline May Lead to a Fishy Body Odor
You might notice a fishy body odor if you take high choline supplements.
This isn’t a good sign. High choline levels can cause diarrhea and sweating, too—all signs that your body is getting too much of a good thing. If you notice any fishy or sweaty smell coming from yourself (or anyone else), talk to your doctor right away. A doctor will help figure out if the problem is caused by too much choline and how to fix it
Diarrhea signifies that your body may have an excess amount of choline.
If you get diarrhea after taking a supplement, you might have taken too much of it. Diarrhea can be caused by a variety of factors and can occur for a variety of reasons. One sign of diarrhea is frequent, loose bowel movements that are often accompanied by pain or cramping in the lower parts of the abdomen.
If you are experiencing these symptoms, you must contact your doctor immediately. In many cases, diarrhea will go away within four days.
Conclusion
Choline is a vital nutrient that plays an essential role in many bodily functions. Men should get 550 mg of choline daily, and women should get 425 mg. You can get choline from meat, fish, eggs, and other foods. But you might want to take choline supplements to get more of this important nutrient or if you need extra help staying healthy.
FAQs about choline supplements
The Institute of Medicine recommends consuming 425 milligrams daily— up to 550 milligrams if you have heart disease or diabetes. If possible, speak with your doctor before taking any new supplements.
Choline can be taken either way, but it will work best if you take it before bedtime.
Choline can cause blood clotting if taken in large amounts. However, it is safe for most people when taken at recommended doses.
Cholinergic neurotransmitters help regulate sleep cycles, attention spans, and muscle movement. They’re also involved in regulating emotions, memory, and cognitive functions. Cholinergic neurotransmiters include acetylcholinesterase (AChE), butyrylcholinesterase, and acetylcholinesterase inhibitors (AChEIs).
Choline deficiency can be caused by eating too little food rich in choline, such as eggs and liver; drinking alcohol excessively; taking certain medications; having an underactive thyroid gland; or having a genetic disorder called methylenetetrahydrofolate reductase (MTHFR).
Choline raises blood pressure when given intravenously. However, it lowers blood pressure when taken orally.
Choline can be taken up into cells within minutes after ingestion.
Alex is a passionate fitness enthusiast dedicated to helping people lead healthier, more active lifestyles. He encourages small – sustainable changes over drastic transformations and works with people to create customized wellness plans. His mission is to help others benefit from the most effective methods available, sharing tips, strategies, and health & fitness tools on Gearuptofit.com to inspire people to live their best lives.